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Old 04-18-2012, 05:55 AM   #1
yksikaksi
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Location: Scandinavia

Join Date: Dec 2009
Posts: 20
Question What is the differences between pre-filtering vs PCR duplicates remove mapped reads?

Hello,

Does is a must to preform pre-filtering for color space reads before mapping?

Could it has a big differences in downstream analysis when I mapped the SOLiD color space reads without pre-filtering but removed the PCR duplicates with Picard tool from mapped reads?

Could anyone kindly please share with me your opinion?

Thank you. Have a nice day.
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