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Old 11-16-2015, 12:50 PM   #5
skbrimer
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Location: OP Kansas

Join Date: Mar 2014
Posts: 53
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Sooo... how does one evaluate an error rate with a reference? Is it just a comparison of the vcf files?

Also why would it be bad to error correct in those situations, I imagine that it will have to due with "correcting" away an actual variant but a variant would still have to be present at a rate higher than the machine's error rate to be called with an confidance right? i.e. if you have a 1% error rate and 1000x coverage you could not call anything less than 10X right?
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