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Old 04-30-2020, 06:26 AM   #5
Junior Member
Location: Netherlands

Join Date: Apr 2020
Posts: 4

Hi GenoMax! Yes, you are right, the fraction of mutations may change in the new pool, but - based on the mixing percentages (in my scenario) - I'll be able to control the level of mutations per position. So, say on position 100, go from 100% MUT to 80% MUT if I mix my original reference fastq and mutated reference fastq using 80/20 percent of reads respectively.
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