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Old 01-06-2010, 10:17 AM   #4
(Jeremy Leipzig)
Location: Philadelphia, PA

Join Date: May 2009
Posts: 116

I think measuring absolute expression in microarrays is very difficult or impossible at the top end of the spectrum. Basically microarrays are only good for ratios, if that.

This article might shed some light on the subject (although I am unable to access it)
Relationship between gene compactness and base composition in rice and human genome. Journal of biomolecular structure & dynamics 2010;27(4):477-88

This subject has interested me since we used to see high viral integration in the very shortest genes, which made for some wacky u-shaped graphs. I'd like to hear more about what you discover.
Jeremy Leipzig
Bioinformatics Programmer
My blog
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