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Old 04-04-2013, 06:18 AM   #8
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Location: East Coast USA

Join Date: Feb 2008
Posts: 7,016

Originally Posted by pmiguel View Post
Did you see the big difference between the top and bottom surface on the error rate plot?

We only have one instrument, so I don't know if it is normal to have that number of bubbles.

The difference was not as dramatic as your plots but the top surface was better. We have several HiSeq's and I have not heard of recurring bubble issues.

You may want to ask your friendly illumina engineer to look at the possibility of a small leak somewhere, specially if you see the bubbles regularly.
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