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Old 04-24-2013, 01:44 AM   #1
Kath
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Location: Oxford

Join Date: Nov 2010
Posts: 24
Default FamSeq vs Polymutt vs DeNovoGear

Hi,

I would like to call variants jointly in a trio, taking pedigree info into account. I have heard of three tools for doing this - FamSeq (http://odin.mdacc.tmc.edu/~wwang7/FamSeqIndex.html), PolyMutt (http://genome.sph.umich.edu/wiki/Polymutt) and DeNovoGear (http://sourceforge.net/projects/denovogear/).

Has anyone used any of these and can they advise me on what are the advantages and disadvantages of each?

Has anyone used any other tools for this?

Thanks!

Kath
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