I have seen duplicate percentage of 33% in targeted high coverage experiment and based on my assessment of false positive and false negative I am happy not removing duplicates.
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Originally posted by husamia View PostI have seen duplicate percentage of 33% in targeted high coverage experiment and based on my assessment of false positive and false negative I am happy not removing duplicates.Mendelian Disorder: A blogshare of random useful information for general public consumption. [Blog]
Breakway: A Program to Identify Structural Variations in Genomic Data [Website] [Forum Post]
Projects: U87MG whole genome sequence [Website] [Paper]
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Originally posted by lh3 View PostIt is possible to dedup before mapping. You may hash the first 14bp of each end and discard a pair if the 14+14bp coincides another pair. This method is not as good as deduping after mapping, but should be good enough. On the other hand, I do not think deduping is quite necessary for assembly.
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Hi. everybody
I have a problem about remove duplicates,
In this study , http://www.ncbi.nlm.nih.gov/Traces/sra/?study=ERP000603
It's have 2 Experiments, and 13 RUNs,
How to do remove duplicates? by study? by Experiments? or by one runs?
Thanks !!
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