Hello Seqers,
we currently do WES with a mean coverage of ~120x for tumor as well as the germline samples. Since we only use the germline to help us with the somatic alteration calls I was thinking about cutting the coverage of the germline samples in half to free up some real estate on the flowcell. Does any one have experience with this?
Thanks, O.
we currently do WES with a mean coverage of ~120x for tumor as well as the germline samples. Since we only use the germline to help us with the somatic alteration calls I was thinking about cutting the coverage of the germline samples in half to free up some real estate on the flowcell. Does any one have experience with this?
Thanks, O.
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