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Old 05-02-2019, 08:47 AM   #1
Jane M
Senior Member
Location: Paris

Join Date: Aug 2011
Posts: 239
Default Lists of somatic mutations from WGS

Dear all,

I am looking for lists of somatic mutations from cohorts of patient (>=50 patients).
There are some discussions about this search (, but I did not identify a good resource/way to get that: I tried using icgc website but -to me- it is unclear if the data are WES or WGS. Also trying using COSMIC (V88_38_NONCODINGVARIANTS.csv) gave weird numbers of somatic mutations per sample...
Thus, I am currently trying to identify publications where the authors released the list of somatic mutations they identified in genomes.
Up to now, I could identify only one such a publication: Zhang et al., Nature Genetics, 2018: A global transcriptional network connecting noncoding mutations to changes in tumor gene expression

Most publications unfortunately do not give this information, they show summaries, hotspots, drivers, or only coding mutations. It should be more systematic in the future, as data reproducibility and availability is of growing interest.

Could you please indicate such publications if you know some of them?
Such a collection might be a useful resource for several of us.

Thank you in advance

Last edited by Jane M; 05-02-2019 at 08:51 AM.
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