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Chipper · 04-12-2011, 11:38 PM

20x is for diploid genomes. But I guess for bacterial genomes it is difficult to get less than 20x coverage anyway even if you multiplex samples (at least for SOLiD and HiSeq).

04-12-2011, 11:38 PM	#4
Chipper Senior Member Location: Sweden Join Date: Mar 2008 Posts: 324	20x is for diploid genomes. But I guess for bacterial genomes it is difficult to get less than 20x coverage anyway even if you multiplex samples (at least for SOLiD and HiSeq).