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Old 08-07-2014, 07:48 PM   #13
Location: USA

Join Date: May 2014
Posts: 24

Thank you for your response.(mikep and mbblack)!!

Q1 : So, are you recommending the "Wilcoxon signed-rank test " instead of GLM model from edgeR or DESeq?? This would not consider the variation like GLM anova analysis...... Do you think is it okay?

Actually, I made the glm model with EdgeR.

design <- model.matrix(~drug)

If you want to publish it standalone, it has to pass the correction.
Q2 : As I mentioned, if I don't have any DEG with correted pvalue, then, I cannot publish the result??? Or can I validate in anyway with DEG filtered with pvalue instead of adjusted p-value for publication?
younko is offline   Reply With Quote