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Old 07-24-2017, 06:14 AM   #2
David Eccles (gringer)
Location: Wellington, New Zealand

Join Date: May 2011
Posts: 838

Heteroplasmy can't exceed 50% unless the analysis is done at a haplotype level (i.e. considering multiple variants). For a single bimorphic variant, a heteroplasmy of greater than 50% would imply that the "other" variant was the dominant allele (and therefore heteroplasmy of less than 50%).
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