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Old 07-21-2016, 01:57 PM   #1
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Location: columbia, missouri

Join Date: Oct 2015
Posts: 7
Default ChIP-seq and Peak calling

I have a simple question that I would like some opinions on. If a transcription factor is highly expressed (protein) in one cell and say now that the expression of is halved because of knock down experiment and you do ChIP-seq on both conditions, would you expect a similar amount peaks found using MACS, or rather a lower level of signal intensity in the knock down condition. I would think just a lower signal, but I'm curious what you all think

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