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Old 08-11-2020, 04:38 PM   #1
Matt.Kanke
Junior Member
 
Location: Chapel Hill, NC

Join Date: Sep 2015
Posts: 4
Default Using scRNA-seq to help with snRNA-seq clustering

Hi,

I am working with a single nucleotide RNA-seq (snRNAseq) dataset. These are often hard to cluster compared to single cell RNA-seq (scRNAseq). I was wondering if you could combine a snRNAseq and scRNAseq using Seurat's integration method, and after assigning clusters, filter out the scRNAseq cells leaving you with (hopefully) better clustered snRNAseq data to continue the analyses.

Thanks,
Matt
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