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  • Announcing: BioDSL - Bioinformatics Domain Specific Language

    BioDSL (pronounced Biodiesel) is a Domain Specific Language for creating bioinformatic analysis workflows. A workflow may consist of several pipelines and each pipeline consists of a series of steps such as reading in data from a file, processing the data in some way, and writing data to a new file.

    BioDSL is build on the same principles as Biopieces, where data records are passed through multiple commands each with a specific task. The idea is that a command will process the data record if this contains the relevant attributes that the command can process. E.g. if a data record contains a sequence, then the command reverse_seq will reverse that sequence.

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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