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Old 09-29-2010, 07:07 AM   #35
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Location: rennes, france

Join Date: Nov 2008
Posts: 7

With the current version we detect only SNPs between individuals. One compares two set of reads, focusing on small substitutions that may be those SNPs.

We are currently working on a version intra-individual, that will enable to detect heterozygous SNP of one individual.

This may be done avoiding the use of a reference genome, if the coverage is sufficient.
Reads of length 50 to 75 are indeed long enougth.

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