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Old 07-28-2017, 05:56 AM   #7
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Location: Cambridge

Join Date: Sep 2010
Posts: 115
Exclamation Any residual DNA-ase in CHIP sample?

Is there any residual DNA-ase left in the CHIP seq DNA sample, after the DNA digestion?

If yes, it can chew back the adapter ends, allowing some of them to ligate into the dimers...
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