Hi all,
I have a general question about how the methylation within the TSS 1000 bp will influence the expression of the gene?
It is easy to understand that if the methylation happens in the same strand as the gene sits, it will potentially repress the expression of the corresponding gene; but if the methylation (within TSS 1000 bp) happens in the + strand, so could it potentially repress the corresponding gene in the - strand as well? Is there any literature about that?
Thanks a lot!
Yao
I have a general question about how the methylation within the TSS 1000 bp will influence the expression of the gene?
It is easy to understand that if the methylation happens in the same strand as the gene sits, it will potentially repress the expression of the corresponding gene; but if the methylation (within TSS 1000 bp) happens in the + strand, so could it potentially repress the corresponding gene in the - strand as well? Is there any literature about that?
Thanks a lot!
Yao
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