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Old 11-09-2008, 07:33 AM   #2
Location: Cambridge, MA

Join Date: Feb 2008
Posts: 82
Default SOLiD Alignment

I have found that it is much better to do any analysis that you can in colorspace before you make the transition to DNA space. We are currently using the SHRiMP (U Toronto) alignment algorithm for fast and accurate alignment in colorspace. But even still 5% seems pretty low for DNA-space alignments of SOLiD data.
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