View Single Post
Old 01-30-2018, 04:42 AM   #2
Senior Member
Location: USA, Midwest

Join Date: May 2008
Posts: 1,169


I'll address the RNA storage question first since that is the easiest. Freezing is just one method for long(ish) term preservation of RNA prior to library prep. RNA Stabilization reagents like RNAlater are very effective and easy to use. Consider the multitude of biologists collecting samples in the field without any ability to freeze tissues or other samples.

Secondly, why would RNA expression analysis NEED to be done in a point of care setting? Consider the situation now. There are probably a multitude of the standard blood tests which could be performed in the Dr.'s office yet they are all performed in a clinical lab. Why wouldn't RNA expression analysis fit into this model just as well?

Finally, it will probably take far longer to develop/discover sufficient clinically meaningful understanding of changes in gene expression to make routine RNA analysis worthwhile than it would to develop the technology you envision.
kmcarr is offline   Reply With Quote