Hi everybody,
I would like to add PhyoP-scores to my SNVs (organism: mouse). I downloaded the following annotations:
http://hgdownload-test.sdsc.edu/gold...y.phyloP60way/
But what is the exact meaning of these scores? I know, that the larger the score the larger is the conservation at that position. But what is the exact range of the PhyloP scores and what is a good threshold for conservation?
Are the phyloP60way files OK to check the conservation or would you recommend any other files?
Thanks
Robby
I would like to add PhyoP-scores to my SNVs (organism: mouse). I downloaded the following annotations:
http://hgdownload-test.sdsc.edu/gold...y.phyloP60way/
But what is the exact meaning of these scores? I know, that the larger the score the larger is the conservation at that position. But what is the exact range of the PhyloP scores and what is a good threshold for conservation?
Are the phyloP60way files OK to check the conservation or would you recommend any other files?
Thanks
Robby
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