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Old 02-25-2014, 10:12 AM   #2
singlemoleculer
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Location: USA

Join Date: Jan 2012
Posts: 8
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One advantage to nanodetector technologies like Oxford and Nabsys is that they are single molecule so you look at individual molecules rather than large pools of identical molecules. Typically, you would not target a specific region but would look at the entire sample that would include the whole genome. I am not aware of any methods for efficiently targeting very long DNAs (other than flow sorting chromosomes or the like). If throughput is high enough, that is not a problem. If throughput is low, it is a problem.
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