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Old 11-02-2010, 06:36 PM   #5
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Location: Palo Alto

Join Date: Apr 2009
Posts: 213

We did so in the U87MG Decoded paper. Ran Illumina 1M-Duo and compared to our SNP calls from WGS on the SOLiD.

I think for these early studies it made sense, but we've reached the point where SNV calls from WGS are more accurate than the error rate of the SNP chips themselves. After that point, all we end up doing is saying, "Well, we did better than a SNP chip," which is kind of silly.
Mendelian Disorder: A blogshare of random useful information for general public consumption. [Blog]
Breakway: A Program to Identify Structural Variations in Genomic Data [Website] [Forum Post]
Projects: U87MG whole genome sequence [Website] [Paper]
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