Hi, all,
Thanks for the help in advance.
I'm looking to alignment program that can handle deep sequencing reads with insertions. Eg. for some of the reads (100bp)
first 50bp is sequence is not from the ref genome, 50bp is sequence from the ref genome.
The break point is variable in each read.
I'm looking for something that can use the mappable sequences in each read to anchor the read to correct region of the genome. This way i'll be able to detect insertions (structural variants) in the sample comparing to the reference genome.
ELANDv2 does the job but it's not free...><
Any suggestions?
Thanks!
Thanks for the help in advance.
I'm looking to alignment program that can handle deep sequencing reads with insertions. Eg. for some of the reads (100bp)
first 50bp is sequence is not from the ref genome, 50bp is sequence from the ref genome.
The break point is variable in each read.
I'm looking for something that can use the mappable sequences in each read to anchor the read to correct region of the genome. This way i'll be able to detect insertions (structural variants) in the sample comparing to the reference genome.
ELANDv2 does the job but it's not free...><
Any suggestions?
Thanks!
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