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We recently purchased an S5 and are planning to bring a test onboard that was done on a proton. The proton using a P1 would consistently give over 90 million total reads. However, on the S5 that same sample using a 540 yields 80 million reads consistently. Is the chemistry different in the proton compared to the S5 or something else? I thought the 540 was comparable to the P1? Is there a way to achieve 90 million reads on the S5? Thanks.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...Yesterday, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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