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Can anyone point me to where I can find public information on the design of the integrated flow cell that Ion Torrent uses in their chips? I don't need great details - basic channel layout and rough dimensions, etc, would be sufficient. From the videos and pics out there it just looks like a molded shell with one inlet and one outlet port and no particular structure in between. Is that all?
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Last edited by BBoy; 03-13-2012, 06:44 PM. -
this thread links to some interesting documents. You can also read their nature paper which goes in to specific details.
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Fabbing a chip washing station??
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Heck no, just curious. I doubt that once set in place by Van der Waals forces there is any type of external agitation that could effectively dislodge a significant number of beads. But if someone comes up with a method it would put a serious dent into Life's consumables revenue stream.Comment
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Has anyone run the Paired-End method yet? I heard there is prep off the instrument to do the enzymatic steps for the second read. If you looked at the beads/reads present in read 1 and then present in read 2 it could give an indication on how well the beads stay in the wells.Comment
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I had you in mind when I asked that question.Originally posted by genseq
This is for another thread, but I would love to hear more about what you're doing, given all the spy documents you post.
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...Today, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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