Hi all,
I'm currently writing an article about sequencing and am trying make fair comparisons between the cost of sequencing 1Mb of DNA on the following machines:
ABI 3730xl (Sanger sequencing)
ABI Solid4hq
Illumina HiSeq2000
Roche 454 GS FLX+
The only manufacturers figures that I can get is for the ABI Solid4hq, which is $33 per Mb (based on their claim of $3000 for sequencing of the human genome at 30X coverage). I'm presuming this includes library prep.
I was wondering if anyone could give me some information about the cost of sequencing on the other machines. Most information that I can find in literature searches is a couple of years old, so I don't feel that I can make a good comparison with current estimates. Also feel free to comment on ABI's estimate above.
Many thanks,
Graham
I'm currently writing an article about sequencing and am trying make fair comparisons between the cost of sequencing 1Mb of DNA on the following machines:
ABI 3730xl (Sanger sequencing)
ABI Solid4hq
Illumina HiSeq2000
Roche 454 GS FLX+
The only manufacturers figures that I can get is for the ABI Solid4hq, which is $33 per Mb (based on their claim of $3000 for sequencing of the human genome at 30X coverage). I'm presuming this includes library prep.
I was wondering if anyone could give me some information about the cost of sequencing on the other machines. Most information that I can find in literature searches is a couple of years old, so I don't feel that I can make a good comparison with current estimates. Also feel free to comment on ABI's estimate above.
Many thanks,
Graham
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