The ability to multiplex a large number of samples in a single run is one of the biggest benefits of using an amplicon-based approach for epidemiological sequencing studies of the SARS-CoV-2 virus as it significantly decreases the turnaround time and cost of analysis. With the ability to multiplex up to 1,536 amplicon libraries in a single run, the NEXTFLEX® DNA-seq kits along with the NEXTFLEX® UDI barcodes deliver a simple, cost-effective solution for adding adapters compatible with Illumina® sequencing to SARS-CoV-2 amplicon pools.
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by seqadmin
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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by seqadmin
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
Channel: Articles
04-04-2024, 04:25 PM -
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