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SRA archive
Hi all,
I have a question regarding experiments in SRA archive. The experiment of my interest has 2 replicates in it. http://www.ncbi.nlm.nih.gov/sra/SRX018610?report=full
I downloaded all of them in a single fastq file by selecting all the runs. The resulting fastq file has combined number of reads of all the replicates. I am planning to do the alignment and peak calling with this single file that has all the reads of replicates.
I was wondering if this is any different from downloading each replicate separately and performing the analysis.
I have a question regarding experiments in SRA archive. The experiment of my interest has 2 replicates in it. http://www.ncbi.nlm.nih.gov/sra/SRX018610?report=full
I downloaded all of them in a single fastq file by selecting all the runs. The resulting fastq file has combined number of reads of all the replicates. I am planning to do the alignment and peak calling with this single file that has all the reads of replicates.
I was wondering if this is any different from downloading each replicate separately and performing the analysis.