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Old 06-26-2012, 01:03 AM   #5
EvilTwin
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Location: Heidelberg

Join Date: Jul 2011
Posts: 8
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@ Heisman,

I just realized I never thanked you for the hint on that paper, but still… thanks a lot!

As I understand, our sequencing core facility had at that time already applied the (or at least some) double-indexing method, so erroneous read assignment should be reduced.

As for the pre-capture pooling, there doesn’t seem to be artificial variant enrichment in the capture pools (e.g. if one sample bears a rare variation, it stays specific for that sample and doesn't show up in the others).
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