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Old 02-25-2019, 11:59 PM   #17
-SB-
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Location: Cambridge

Join Date: Nov 2014
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Thing is - that we all love epigenetics (particularly the CEGX contribution) or the dinky little machines coming out from Illumina, yes microarrays are pretty - and you can't beat a lovely biome study ... ... CRISPr provides us with a theoretically infinite capacity to generate data ... .. and the current drive towards dedifferentiation/differentiation in stem cells is wonderful too - but we now know all of the answers (we knew this day would come) if we'd just choose to put everything that we've accumulated to date together.

Simply - there's a process of autophagy which clears disease.
Being worked up in Oxford and Cambridge by Yun Zhang and David Rubinsztein, respectively.
All that's required is to study the biology of FASTing.
Valter Longo (Longevity Institute) has based his career on this idea.

Now ... ... simplifying into one line (all of the above techniques we love) and just to illustrate.

FED -> IIS network gene expression -> fixed in place through epigenetic modification -> altered biome (low diversity) -> disease (damage accumulation)
CEGX are working up the transition from one network being switched on to the other network being switched on ie the way that the 'switch' works or methylation -> removal of methylation.
FASTED -> ToR network gene expression -> fixed in place through epigenetic modification -> altered biome (diversity) -> health (via stem cell reactivation replenishment of damaged cells/components)

Last edited by -SB-; 02-26-2019 at 12:07 AM.
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