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Old 10-14-2016, 09:10 AM   #8
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Location: SF Bay Area, CA, USA

Join Date: Oct 2007
Posts: 1,358

@Genomax...the logical explanation is that the SMRTcell production process is dramatically more complicated than all other sequencing consumables, ZMW size and uniformity, the micromirror shape, aluminum coating, then on top of that the blocking of the surface and then the biotinylation.

I know it's no solace to scientists trying to do reproducible production (we run two RSII's all the time), but it's kind of amazing just how well it all works, and is a testament to all the people that have contributed at PACB. (disclaimer I worked there for a long time and know a lot of people there still)
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