SEQanswers - View Single Post - Calling tumor CNVs without normal as control?

bw. · 11-05-2013, 02:11 AM

Also curious about this. Perhaps they are using pooled normals?
If library prep & sequencer are the same, and the pooled samples are copy-number neutral, it should be possible to get decent results using ExomeCNV.

11-05-2013, 02:11 AM	#2
bw. Member Location: San Francisco, CA Join Date: Mar 2012 Posts: 21	Also curious about this. Perhaps they are using pooled normals? If library prep & sequencer are the same, and the pooled samples are copy-number neutral, it should be possible to get decent results using ExomeCNV.