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Old 09-13-2011, 08:01 AM   #2
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Location: Germany

Join Date: Oct 2008
Posts: 415

We tried one called Nesoni to correct bacterial 454 contigs using Illumina short read data. It worked ok and corrected about 50 errors in a 6MB genome (if I remember rightly).

We haven't continued with this approach extensively, your 300 MB sounds like a lot more of a challenge.
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