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Old 01-03-2012, 08:09 AM   #6
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Location: Phoenix, AZ

Join Date: Mar 2010
Posts: 279

Gene sizes can be downloaded for most organisms using the BioMart tool on ensembl, or but not my favorite source UCSC using the table browser. I suspect you are good just normalizing to either the coding region or full mRNA space but I'd vote for coding if the question is about consequential changes that are easy to understand. Take a look at Wood et al. Science 318:1108 (2007) for a nice example of this type of analysis
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