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Old 03-04-2019, 05:35 AM   #6
Location: Boston

Join Date: Mar 2019
Posts: 11

I can't help much in that regard since I only work with microbial samples, but it should be clear from literature what most people use. I honestly don't think you need RNAlater, but I also don't think it would hurt (if it did, there should be a publication on it). There was a paper from, I think, the mid 90's that looked at the stability of samples flash frozen vs. RNAlater and demonstrated better RNA quality when stored at 4 degC and room temperature. They weren't using the commercial RNAlater, but came up with the formulation themselves (this was before RNAlater was a product).
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