Hi all,
We have performed whole genome sequencing(WGS) in 6 affected individuals and 2 parent samples to identify the causal variant for a particular phenotype. The disease is known to inherit by recessive mode.
For all the samples we have the SNP's identified by WGS analysis in VCF format. Could someone suggest a method/tool to perform linkage analysis to map a specific region/gene to the phenotype?
Any suggestions are valuable!!
We have performed whole genome sequencing(WGS) in 6 affected individuals and 2 parent samples to identify the causal variant for a particular phenotype. The disease is known to inherit by recessive mode.
For all the samples we have the SNP's identified by WGS analysis in VCF format. Could someone suggest a method/tool to perform linkage analysis to map a specific region/gene to the phenotype?
Any suggestions are valuable!!
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