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Old 08-08-2013, 06:20 AM   #1
NGS group
Location: Netherlands

Join Date: Apr 2013
Posts: 28
Question How to incorporate the reference into SNP tree

Hi everyone,

I am trying to build a SNP tree. The principle is to extract SNPs from each sample mapped to the reference to get a pseudo "SNP genome", and then multi-alignment will be performed with all "SNP genomes". However, there is no SNP can be extracted from the reference mapping to itself. Therefore, the question is how to incorporate the reference into the SNP tree?

Thank you very much in adavance!

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