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Old 08-13-2013, 11:27 PM   #2
Simon Anders
Senior Member
Location: Heidelberg, Germany

Join Date: Feb 2010
Posts: 994

No, paired-end is not better in accuracy. At least, for simple differential expression analysis, it does not make much of a difference.

As for your question, the answer is: It depends.

Hence, please always give details on your experimental design when posting a question here,
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