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Old 09-25-2013, 11:03 PM   #1
Kennels
Senior Member
 
Location: Sydney

Join Date: Feb 2011
Posts: 149
Default edgeR BCV plot interpretation

Hi,

Would someone be so kind as to help me interpret this BCV plot (in somewhat laymans terms) generated from edgeR? It is based on RNA-seq data (expected counts from RSEM) from 2 samples and 1 control.
My take is that at low counts there is very high variability, but I can't tell if this is good or bad in terms for downstream analysis, as the plot is quite different from the ones in the edgeR manual, and there is a 'dip' at logCPM of around 1.

By the way, the CommonDispersion was:
Disp = 0.2688 , BCV = 0.5185

thank you
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