Just saw this article over at In Sequence, and wanted to see what people thought about it as I'd never heard of this company.
The company is OpGen, and they have a patent suite concerned with methods to produce "optical restriction maps" of microbial genomes. From briefly perusing a couple of the main patents...
...they basically can generate high resolution (and/or single molecule) restriction maps of small genomes. With the appropriate mix of restriction enzymes, this can act as fine structural mapping necessary to properly finish most genome sequencing projects. They are concentrating on small genomes as there are undoubtedly limits to the technology as genome size increases.
The company is OpGen, and they have a patent suite concerned with methods to produce "optical restriction maps" of microbial genomes. From briefly perusing a couple of the main patents...
...they basically can generate high resolution (and/or single molecule) restriction maps of small genomes. With the appropriate mix of restriction enzymes, this can act as fine structural mapping necessary to properly finish most genome sequencing projects. They are concentrating on small genomes as there are undoubtedly limits to the technology as genome size increases.
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