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Old 06-06-2011, 06:34 PM   #7
Location: FL

Join Date: Mar 2011
Posts: 54

Does removal of PCR duplicates mean that all the reads are removed or only one read is kept?

If only one read is kept, then it won't influence the de novo assembling result no matter removing PCR duplicates or not. If all the reads are removed, then bias is created.
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