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Old 01-27-2014, 10:11 AM   #18
Simon Anders
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Location: Heidelberg, Germany

Join Date: Feb 2010
Posts: 994
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Quote:
Originally Posted by rskr View Post
I don't think FDR is very important for RNA-seq.
Sorry, I cannot let this stand like this, as it might be misunderstood to mean that accounting for multiple hypothesis testing is optional in RNA-Seq data analysis. Of course, you always need to account for multiple hypothesis testing when you test many hypothesis (here: many genes).

Quote:
On the flip side, you could get a fabulous FDR, by simply not sequencing very much.
Um, no, you don't. Why should you?
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