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Old 03-20-2014, 07:24 AM   #1
Gorbenzer
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Location: italy

Join Date: Apr 2012
Posts: 45
Default MIRA 4 poor performance compared to 3.9.X

Dear all,
i'm having big issues using MIRA 4 for bacterial denovo sequencing: number of contigs generated by assembly with MIRA 4 is insanely higher than with MIRA 3.9.X.

Here are some comparison of number of contigs generated by assembly with the two MIRA versions:

MIRA 3.9.15 ---> MIRA 4

38 ---> 252
44 ---> 168
74 ---> 236
48 ---> 206


All these datasets are of good quality and give between 50X and 100X coverage.


Anyone knows the cause of this? Maybe some kind of default setting that was changed and now need to be manually set?
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