Hi,
My current project involves mapping short reads to the reference genome from another species (reads and reference genome belong to the same genus), e.g. mapping chimp reads to human genome. I want to know if this type of mapping is possible and if it is possible, Do the results has any meaning?
In other words, I want to know whether current short reads mapping algorithms (BWA, MAQ etc.) can give useful results when deal with somewhat distant genomes (same genus but different species)?
Many thanks
--Hao
My current project involves mapping short reads to the reference genome from another species (reads and reference genome belong to the same genus), e.g. mapping chimp reads to human genome. I want to know if this type of mapping is possible and if it is possible, Do the results has any meaning?
In other words, I want to know whether current short reads mapping algorithms (BWA, MAQ etc.) can give useful results when deal with somewhat distant genomes (same genus but different species)?
Many thanks
--Hao
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