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MosaikText can convert a mosaik output into either SAM or BAM files; however, it always produces a zipped output. Is there a way to make it produce one of these formats without gzipping it?
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correction: the BAM file produced my mosaik can be used as is. -
Gambit crashes with .bam file from Mosaik
The visualization software Gambit crashes when I attempt to open my .bam file created using Mosaik (MosaikText). Does anyone else have this problem? I am able to open the .ace file using consed, but I'd like to try Gambit.Comment
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I recently used MOSAIK to align my short Illumina reads and had the -m unique parameter initialized, but when I convert the map file to .sam format, I see reads that aligned to multiple places. Does anyone understand this?Comment
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM -
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...04-04-2024, 04:25 PM
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