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adaptivegenome · 02-17-2012, 04:39 PM

Realignment is performed on a set of reads. If you merge two BAMs and add reads to a locus then realignment is needed. Same goes for marking duplicates or recalibrating bases.

02-17-2012, 04:39 PM	#2
adaptivegenome Super Moderator Location: US Join Date: Nov 2009 Posts: 437	Realignment is performed on a set of reads. If you merge two BAMs and add reads to a locus then realignment is needed. Same goes for marking duplicates or recalibrating bases. Last edited by adaptivegenome; 02-17-2012 at 04:39 PM. Reason: typo