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Old 01-09-2012, 12:26 AM   #2
simonandrews
Simon Andrews
 
Location: Babraham Inst, Cambridge, UK

Join Date: May 2009
Posts: 871
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These sorts of pattern are pretty common (almost to the point of being universal) in RNA-Seq libraries. Apparently it's the 'random' hexamer priming which isn't as random as you might hope.
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