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  • Creating Circular genome map

    Could any one suggest me how to create a circular genome map with read coverage track. Thanks in advance.

  • #2
    See if this will help: http://www.bcgsc.ca/platform/bioinfo/software/circos

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    • #3
      @GenoMax,
      Thanks I will check

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      • #4
        Circos is probably the most commonly used one.

        Others include

        CGview (http://wishart.biology.ualberta.ca/cgview/)
        DNAPlotter (http://bioinformatics.oxfordjournals.../25/1/119.full)
        GenomeViz (http://www.biomedcentral.com/1471-2105/5/198)
        Marco

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        • #5
          You can also use GenomeDiagram in Biopython to draw a circular genome with a coverage depth plot round it - but this is a programmatic interface.

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          • #6
            BRIG looks quite nice, haven't used it yet though

            Download BLAST Ring Image Generator for free. BRIG is a cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. Please cite the BRIG paper if BRIG is used to generate figures for publications: NF Alikhan, NK Petty, NL Ben Zakour, SA Beatson (2011) BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons, BMC Genomics, 12:402.

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            • #7
              BUMPED.

              Thank you for this. We're using CLC Bio for routine analysis (which is really nice) but it doesn't support circular genome maps at the moment.

              So far BRIG has done what I need. CIRCOS looks gorgeous, after 2 hours installing and configuring all the perl libraries needed to support it, I caved and gave up. Maybe I try again in a week or so.
              @bioinformer
              http://www.linkedin.com/in/jonathanjacobs

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              • #8
                circos

                I have to plot a seq uencing data in circle and wonder what tool wil be used. I found Circos but is not window based and intutive for a biologist. Is there a version of CIRCOS which can be easily used or any alternative tool. It is a human genome based data.

                Thanks

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                • #9
                  Regarding DNAplotter

                  Hello everyone

                  I have done re-sequencing of one of Vibrio cholerae strain and has data in form of consensus sequence for both the chromosomes. Now I want to make these consensus circular and compare them with the reference . Is it possible to do that with DNAplotter? I mean I want that outer circle should be my reference sequence and the inner circle should me my consensus sequence.

                  I am trying to use DNAplotter but not getting much. please pardon me if I am missing something very obvious.

                  Regards,
                  Neha
                  Last edited by neha; 07-19-2012, 09:16 PM.

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