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Old 09-22-2008, 03:11 AM   #2
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Location: Poznan, Poland

Join Date: Jul 2008
Posts: 6

What we are doing is to apply kind of quantile normalization. After to obtain a score for each miRNA , since we are expecting that most of the miRNA have similar expression in both tissues at study, we normalize the score values to have similar distribution.

The main reason to apply this kind of normalization is that we were very worry about the different coverage of the different samples at study.
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